In Parkinson’s disease (PD), the progressive neuromotor disorder of central nervous system, patients often complain of gut problems, issues that can precede a diagnosis by decades.

Coincidence or something more?

Enter the gut-brain axis, a superhighway tracking a complex relationship between the gut microbiome and  nervous system.

A recent article from the International Probiotics Association delved into Parkinson’s disease expressions: loss of dopaminergic neurons and a buildup of alpha-synuclein in surviving neurons. They found in the research that neuroinflammation and reactive oxidative species production favor accumulation. And both are linked to microbial imbalance.

Probiotics Show Promise in Parkinson’s Disease appears in Whole Foods magazine online.

The article reviews various lines of inquiry according to IPA: